Istradefylline 40 mg/day increased peak concentrations and AUC of CYP3A4 substrates in scientific trials. This effect was not noticed with istradefylline twenty mg/working day. Think about dose reduction of sensitive CYP3A4 substrates.Hou et al (2005) studied the autonomic results of modafinil in human beings. They found that modafinil influences t… Read More